The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 prevents reinstatement of extinguished ethanol-induced conditioned place preference in mice

► mGluR7 is involved in ethanol conditioned reward. ► mGluR7 modulation did not affect ethanol CPP extinction. ► AMN082, but not MMPIP, reduced ethanol CPP reinstatement. ► MMPIP reversed AMN082 effect on EtOH-CPP reinstatement.