Guamanian Suncus murinus responsiveness to emetic stimuli and the antiemetic effects of 8-OH-DPAT

► Guamanian Suncus are less susceptible to motion compared to Japanese Suncus. ► Guamanian Suncus are more susceptible to nicotine compared to Japanese Suncus. ► Guamanian Suncus require less 8-OH-DPAT for emetic relief than Japanese Suncus. ► Guamanian Suncus are smaller and more aggressive than Japanese Suncus. ► Guamanian Suncus are an acceptable and effective model for emetic research.