An acetaldehyde-sequestering agent inhibits appetitive reinforcement and behavioral stimulation induced by ethanol in preweanling rats

►Ethanol induced tactile appetitive conditioning in infant rats. ►Ethanol induced motor behavioral stimulation in infant rats. ►Systemic administration of d-penicillamine (DP) blocked the conditioning. ►Central administration of DP blocked ethanol's motor activating effects. ►Acetaldehyde mediates ethanol's motivational effects in infant rats.