کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10884011 1078823 2005 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
چکیده انگلیسی
Cell-penetrating peptides (CPPs) have been used to overcome the lipophilic barrier of the cellular membranes and deliver large molecules and even small particles inside the cell for their biological actions. CPPs are being used to deliver inside cell a large variety of cargoes such as proteins, DNA, antibodies, contrast (imaging) agents, toxins, and nanoparticular drug carriers including liposomes. In this paper, we have reviewed the delivery of different molecules and particles mediated by TAT, Antp, VP22, and other CPPs as well as potential applications of these delivery systems in different areas of vaccine development, cancer immunotherapy, gene delivery, and cellular imaging.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 57, Issue 4, 28 February 2005, Pages 637-651
نویسندگان
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