کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10962708 | 1102648 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Influenza vaccine effectiveness in Italy: Age, subtype-specific and vaccine type estimates 2014/15 season
ترجمه فارسی عنوان
اثربخشی واکسن آنفلوانزا در ایتالیا: سن، نوع خاص و نوع واکسن تخمینی 2014/15 فصل
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کلمات کلیدی
آنفلوانزا، اثربخشی واکسن، آزمایش های منفی مورد بررسی کنترل،
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Within the context of the existing National sentinel influenza surveillance system (InfluNet) a test-negative case-control study was established in order to produce vaccine effectiveness (VE) estimates. The point estimates VE were adjusted by age group (<5; 5-15; 15-64; 65+ years), the presence of at least one chronic condition, target group for vaccination and need help for walking or bathing. In Italy, adjusted estimates of the 2014/15 seasonal influenza VE against medically attended influenza-like illness (ILI) laboratory-confirmed as influenza for all age groups were 6.0% (95%CI: â36.5 to 35.2%), 43.6% (95%CI: â3.7 to 69.3%), â84.5% (95%CI: (â190.4 to â17.2%) and 50.7% (95% CI: â2.5 to 76.3%) against any influenza virus, A(H1N1)pdm09, A(H3N2) and B, respectively. These results suggest evidence of good VE against A(H1N1)pdm09 and B viruses in Italy and evidence of lack of VE against A(H3N2) virus due to antigenic and genetic mismatch between circulating A(H3N2) and the respective 2014/15 vaccine strain.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 34, Issue 27, 8 June 2016, Pages 3102-3108
Journal: Vaccine - Volume 34, Issue 27, 8 June 2016, Pages 3102-3108
نویسندگان
Caterina Rizzo, Antonino Bella, Valeria Alfonsi, Simona Puzelli, Anna Pina Palmieri, Maria Chironna, Elena Pariani, Alessandra Piatti, Donatella Tiberti, Valeria Ghisetti, Roberto Rangoni, Maria Eugenia Colucci, Paola Affanni, Cinzia Germinario,