کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10963355 1102679 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of vaccines for Plasmodium vivax malaria
ترجمه فارسی عنوان
توسعه واکسن برای پلاسمودیوم ویواکس مالاریا
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
چکیده انگلیسی
Plasmodium vivax continues to cause significant morbidity outside Africa with more than 50% of malaria cases in many parts of South and South-east Asia, Pacific islands, Central and South America being attributed to P. vivax infections. The unique biology of P. vivax, including its ability to form latent hypnozoites that emerge months to years later to cause blood stage infections, early appearance of gametocytes before clinical symptoms are apparent and a shorter development cycle in the vector makes elimination of P. vivax using standard control tools difficult. The availability of an effective vaccine that provides protection and prevents transmission would be a valuable tool in efforts to eliminate P. vivax. Here, we review the latest developments related to P. vivax malaria vaccines and discuss the challenges as well as directions toward the goal of developing highly efficacious vaccines against P. vivax malaria.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 33, Issue 52, 22 December 2015, Pages 7489-7495
نویسندگان
, , ,