کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10964461 | 1102715 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A national reference for inactivated polio vaccine derived from Sabin strains in Japan
ترجمه فارسی عنوان
یک مرجع ملی برای واکسن غیرفعال فلج اطفال مشتق شده از سوابین در ژاپن
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کلمات کلیدی
OPVVDPVIPVDTaPVAPPSDUVaccine-derived poliovirusesCIPVNIIDCCID50World Health Organization - سازمان بهداشت جهانیVaccine-associated paralytic poliomyelitis - سندرم تخمدان پلی کیستیOral polio vaccine - واکسن فلج اطفالinactivated polio vaccine - واکسن فلج اطفال غیر فعال شدهpoliomyelitis - پولیوئیدWHO - که
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
As one aspect of its campaign to eradicate poliomyelitis, the World Health Organization (WHO) has encouraged development of the inactivated polio vaccine (IPV) derived from the Sabin strains (sIPV) as an option for an affordable polio vaccine, especially in low-income countries. The Japan Poliomyelitis Research Institute (JPRI) inactivated three serotypes of the Sabin strains and made sIPV preparations, including serotypes 1, 2 and 3 D-antigens in the ratio of 3:100:100. The National Institute of Infectious Diseases, Japan, assessed the immunogenic stability of these sIPV preparations in a rat potency test, according to an evaluation method recommended by the WHO. The immunogenicity of the three serotypes was maintained for at least 4 years when properly stored under â70 °C. Based on these data, the sIPV preparations made by JPRI have been approved as national reference vaccines by the Japanese national control authority and used for the quality control of the tetracomponent sIPV-containing diphtheria-tetanus-acellular pertussis combination vaccines that were licensed for a routine polio immunization in Japan.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 32, Issue 40, 8 September 2014, Pages 5163-5169
Journal: Vaccine - Volume 32, Issue 40, 8 September 2014, Pages 5163-5169
نویسندگان
Haruko Shirato, Yuichi Someya, Masaki Ochiai, Yoshinobu Horiuchi, Motohide Takahashi, Naokazu Takeda, Kengo Wakabayashi, Yasumitsu Ouchi, Yoshihiro Ota, Yoshio Tano, Shinobu Abe, Shudo Yamazaki, Takaji Wakita,