کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10964942 | 1102730 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Long-term viremia and fecal shedding in pups after modified-live canine parvovirus vaccination
ترجمه فارسی عنوان
پسوریازیس طولانی مدت و دفع مدفوع در نوزادان پس از واکسیناسیون پاروویروس مجله زندگی مجدد زنده
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
پاروویروس سگ، واکسیناسیون، ریزش ویروس، وایریمیا،
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
چکیده انگلیسی
Canine parvovirus (CPV) modified live virus vaccines are able to infect vaccinated dogs replicating in the bloodstream and enteric mucosa. However, the exact duration and extent of CPV vaccine-induced viremia and fecal shedding are not known. With the aim to fill this gap, 26 dogs were administered two commercial vaccines containing a CPV-2 or CPV-2b strain and monitored for 28 days after vaccination. By using real-time PCR, vaccine-induced viremia and shedding were found to be long lasting for both vaccinal strains. Vaccinal CPV-2b shedding was detected for a shorter period than CPV-2 (12 against 19 mean days) but with greater viral loads, whereas viremia occurred for a longer period (22 against 19 mean days) and with higher titers for CPV-2b. Seroconversion appeared as early as 7 and 14 days post-vaccination for CPV-2b and CPV-2 vaccines, respectively. With no vaccine there was any diagnostic interference using in-clinic or hemagglutination test, since positive results were obtained only by fecal real-time PCR testing. The present study adds new insights into the CPV vaccine persistence in the organism and possible interference with diagnostic tests.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 32, Issue 30, 24 June 2014, Pages 3850-3853
Journal: Vaccine - Volume 32, Issue 30, 24 June 2014, Pages 3850-3853
نویسندگان
Nicola Decaro, Giuseppe Crescenzo, Costantina Desario, Alessandra Cavalli, Michele Losurdo, Maria Loredana Colaianni, Gianpiero Ventrella, Stefania Rizzi, Stefano Aulicino, Maria Stella Lucente, Canio Buonavoglia,