A systematic review of safety data reporting in clinical trials of vaccines against malaria, tuberculosis, and human immunodeficiency virus

► We reviewed safety reporting in 124 malaria, TB and HIV vaccine trial publications. ► Vaccine safety reporting was highly non-standardized and often lacked key data. ► 269 generally undefined and overlapping terms were used to describe adverse events. ► Standardized safety reporting should be a requirement for vaccine trial publication.