What the World's religions teach, applied to vaccines and immune globulins

► Religion-based objections to vaccination date to circa 1796. ► Over 60 vaccine-preventable outbreaks in religious settings have been described. ► Ostensibly religious reasons to decline vaccination may mask safety questions. ► Acceptability may hinge on transformation, dilution, purpose, and alternatives. ► Important reasons to vaccinate include preserving health and duty to community.