Recombinant heat shock protein 60 (Hsp60/GroEL) of Salmonella enterica serovar Typhi elicits cross-protection against multiple bacterial pathogens in mice

► Studied cross-protectivity of recombinant S. Typhi GroEL against other microbes. ► in vitro, in vivo result showed significant protection against bacterial pathogen. ► S. Typhi GroEL protected not only Typhoid but also the other bacterial diseases.