Vitamin D deficiency is associated with poor response to active hepatitis B immunisation in patients with chronic kidney disease

► Patients suffering from chronic kidney disease respond poorly to hepatitis B vaccination. ► Vitamin D deficiency is highly prevalent in these patients. ► Low vitamin D levels are associated with failure to achieve seroconversion. ► Antibodies were lower in vitamin D deficient patients. ► Treatment with calcitriol is not associated with a better response to vaccination.