Sendai virus-based RSV vaccine protects African green monkeys from RSV infection

► SeVRSV, a recombinant Sendai virus expressing RSV F, was tested in AGM. ► SeVRSV elicited antibody responses against SeV and RSV. ► SeVRSV fully protected AGM from lower respiratory tract RSV infection. ► SeVRSV caused no clinically relevant adverse events. ► SeVRSV is an attractive RSV vaccine candidate.