The impact of making vaccines thermostable in Niger's vaccine supply chain

► HERMES computational simulation model of Niger's vaccine supply chain. ► Simulated the impact of making different combinations of vaccines thermostable. ► Making any EPI vaccine thermostable relieved existing supply chain bottlenecks. ► Making any EPI vaccine thermostable increased vaccine availability of all vaccines. ► The most substantial impact came from making the pentavalent vaccine thermostable.