Anti-inflammatory activity of sublingual immunoglobulin (SLIG) in a murine model of allergen-driven airway inflammation

► Sublingual immunoglobulin (SLIG) is anti-inflammatory in mice with allergen-driven airway inflammation. ► The anti-inflammatory activity of SLIG is independent of the Ig specificity. ► This activity is not related to a marked change in Th2, Th17 or T regulatory cells.