کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10967945 1102856 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Mucosal vaccination increases local chemokine production attracting immune cells to the stomach mucosa of Helicobacter pylori infected mice
چکیده انگلیسی
► Sublingual vaccination protects against H. pylori infection in the stomach. ► The relationship between vaccine-induced gastric chemokine responses and protection against H. pylori infection is not known. ► Vaccination strongly induced chemokines in the stomach known to attract eosinophils, T cells and neutrophils. ► Protection coincided with accumulation of CD4+ T cells, eosinophils, neutrophils and CD103+ dendritic cells in the stomach. ► Our results will guide in the testing of vaccines against H. pylori infection in humans.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 30, Issue 9, 21 February 2012, Pages 1636-1643
نویسندگان
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