Immunization with the recombinant antigen Ss-IR induces protective immunity to infection with Strongyloides stercoralis in mice

► Mice immunized with Ss-IR antigen develop resistance to Strongyloides stercoralis. ► Ss-IR antibodies were localized to the parasite surface and glandular esophagus. ► Serum collected from immunized mice passively transferred immunity. ► Ss-IR may be suitable as a vaccine against human strongyloidiasis.