Challenges in dendritic cells-based therapeutic vaccination in HIV-1 infection

► Monocyte-derived DCs (MD-DCs) with HIV-1 antigens as therapeutic vaccination. ► The design of the clinical trials varies greatly between groups. ► The results indicate that DC immunotherapy elicits immunological responses. ► A panel of experts in DC-based clinical trials in HIV-1 met at the end of 2010. ► This report summarizes the situation of the field and conclusions of this meeting.