کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10968613 | 1102896 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effectiveness of the whole-cell pertussis vaccine produced in Poland against different Bordetella parapertussis isolates in the mouse intranasal challenge model
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
⺠The effectiveness of the whole-cell pertussis vaccine produced locally and routinely used in Poland against Bordetella parapertussis strains from the lungs and trachea of a mouse model was studied. ⺠The effectiveness of B. parapertussis elimination rates from the lungs of whole-cell pertussis immunized mice was found to be lower than against Bordetella pertussis isolates. ⺠The average protective effect of whole-cell pertussis vaccine comparing with acellular one against B. parapertussis in the lungs of mice was significantly higher. ⺠The level of protection and course of B. parapertussis infection in the lungs and trachea seemed to be strain specific.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 29, Issue 33, 26 July 2011, Pages 5488-5494
Journal: Vaccine - Volume 29, Issue 33, 26 July 2011, Pages 5488-5494
نویسندگان
Monika Zawadka, Maciej Polak, Daniel Rabczenko, Ewa Mosiej, Ewa Augustynowicz, Anna LutyÅska,