کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10969174 | 1102926 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The effect of rotavirus immunization on rotavirus gastroenteritis hospitalization rates in military dependents
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The effect of rotavirus immunization on rotavirus gastroenteritis hospitalization rates in military dependents The effect of rotavirus immunization on rotavirus gastroenteritis hospitalization rates in military dependents](/preview/png/10969174.png)
چکیده انگلیسی
We conducted a retrospective review of all U.S. military dependents less than 5 years old hospitalized with rotavirus-associated gastroenteritis from July 2003 to June 2009. The two post-vaccine seasons showed a significant reduction of 62.4% (95% CI, 58.6-65.8, PÂ <Â 0.001) in rotavirus gastroenteritis hospitalization rate compared to the three pre-vaccine seasons. Infants less than 12 months old showed the greatest reduction in incidence at 75.3%. A substantial decrease was also seen in unvaccinated children as well. Vaccine efficacy against hospitalization was 86.0% (95% CI, 77.7-91.3) after just a single dose. The overwhelming majority of children hospitalized for rotavirus since the introduction of the vaccine (ranging from 91.8 to 100% per season) had not received any of the rotavirus vaccine series.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 29, Issue 4, 17 January 2011, Pages 650-659
Journal: Vaccine - Volume 29, Issue 4, 17 January 2011, Pages 650-659
نویسندگان
Matthew D. Eberly, Greg H. Gorman, Matilda B. Eide, Cara H. Olsen, Michael Rajnik,