Plant expressed EtMIC2 is an effective immunogen in conferring protection against chicken coccidiosis

► Eimeria tenella Microneme 2 (EtMIC2) gene was clones from sporozoite RNA. ► The gene was transiently expressed in tobacco and characterized immunologically. ► Efficacy of recombinant EtMIC2 in bird challenege experiment was evaluated. ► Plant expressed antigen confer partial protection to immunized birds.