Development of an inactivated candidate vaccine against Chandipura virus (Rhabdoviridae: Vesiculovirus)

► Chandipura virus (Rhabdoviridae: Vesiculovirus) is an encephalitis causing virus of the pediatric group with high case fatality rate. ► A candidate vaccine against the virus is developed and evaluated. ► Beta propio lactone-the vaccine produces 100% sero-conversion in Swiss albino mice. ► Neutralizing antibody after the third dose ranged from 1:80 to 1:320. ► Mice with antibody titer >20 survived intra cranial virus challenge.