کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11006298 | 1501644 | 2019 | 35 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis, spectral and crystallographic study, DNA binding and molecular docking studies of homo dinuclear Co(II) and Ni(II) complexes
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
Two homo dinuclear metal complexes with composition [M2(pda)2(H2O)5]·2H2O (Mâ¯=â¯Ni2+ and Co2+) have been synthesized and characterized by elemental, spectral and thermal analysis (UV-vis, FT-IR, Fluorescence, EPR, and TGA). The structures of complexes 1 and 2 have been determined by single crystal X-ray diffraction studies and the geometry around M(II) ion was elongated distorted octahedral. Binding studies of the complexes 1 and 2 with Ct-DNA was investigated by absorption, fluorescence and viscosity measurements. The experimental results of DNA binding studies were supported by theoretical (molecular docking analysis). DNA binding results reveal that complexes 1 and 2 bind to the minor groove of DNA and are stabilized through hydrogen bonding interactions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 1175, 5 January 2019, Pages 889-899
Journal: Journal of Molecular Structure - Volume 1175, 5 January 2019, Pages 889-899
نویسندگان
M. Shahnawaz Khan, Mohd Khalid, M. Shahwaz Ahmad, Musheer Ahmad, Mo Ashafaq, Rahisuddin Rahisuddin, Rizwan Arif, M. Shahid,