کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11033847 1568226 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Statistical methods for detecting admixture
ترجمه فارسی عنوان
روش های آماری برای تشخیص مخلوط
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
چکیده انگلیسی
The increasing availability of large-scale autosomal genetic variation data sampled from world-wide geographic areas, coupled with advances in the statistical methodology to analyse these data, is showcasing the power of DNA as a major tool to gain insights into the demographic history of humans and other organisms. Here we review statistical techniques that shed light on a specific aspect of demography: the detection and description of admixture events where two or more genetically distinct groups intermixed at one or more times in the past. In particular we give an overview of some of the widely used methods to identify and describe admixture events using autosomal DNA from unrelated individuals, with a particular focus on analysing biallelic Single-Nucleotide-Polymorphsim (SNP) markers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 53, December 2018, Pages 121-127
نویسندگان
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