کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1164029 1490967 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Organic solvent and temperature-enhanced ion chromatography-high resolution mass spectrometry for the determination of low molecular weight organic and inorganic anions
ترجمه فارسی عنوان
حلال های آلی و کروماتوگرافی یونی با افزایش دما با استفاده از طیف سنجی جرمی با وضوح بالا برای تعیین وزن کم مولکولی آنون های آلی و معدنی
کلمات کلیدی
کروماتوگرافی یونی، طیف سنجی جرمی با وضوح بالا، حلال الی، درجه حرارت، آنیون ها
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• IC selectivity at high contents of organic solvent in eluent and elevated temperature is studied.
• Solvent-enhanced IC coupled to high resolution MS is beneficial for sensitive detection of ions.
• The first application of IC-HRMS to the detection of low explosives in fingermarks is shown.

There has recently been increased interest in coupling ion chromatography (IC) to high resolution mass spectrometry (HRMS) to enable highly sensitive and selective analysis. Herein, the first comprehensive study focusing on the direct coupling of suppressed IC to HRMS without the need for post-suppressor organic solvent modification is presented. Chromatographic selectivity and added HRMS sensitivity offered by organic solvent-modified IC eluents on a modern hyper-crosslinked polymeric anion-exchange resin (IonPac AS18) are shown using isocratic eluents containing 5–50 mM hydroxide with 0–80% methanol or acetonitrile for a range of low molecular weight anions (<165 Da). Comprehensive experiments on IC thermodynamics over a temperature range between 20–45 °C with the eluent containing up to 60% of acetonitrile or methanol revealed markedly different retention behaviour and selectivity for the selected analytes on the same polymer based ion-exchange resin. Optimised sensitivity with HRMS was achieved with as low as 30–40% organic eluent content. Analytical performance characteristics are presented and compared with other IC-MS based works. This study also presents the first application of IC-HRMS to forensic detection of trace low-order anionic explosive residues in latent human fingermarks.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 865, 20 March 2015, Pages 83–91
نویسندگان
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