کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1164091 1490974 2015 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A simple method for patterning poly(dimethylsiloxane) barriers in paper using contact-printing with low-cost rubber stamps
ترجمه فارسی عنوان
یک روش ساده برای تدوین موانع پلی (دی متیل سیلوکسان) در کاغذ با استفاده از چاپ تماس با تمبرهای ارزان قیمت
کلمات کلیدی
دستگاه های تحلیلی مبتنی بر کاغذ، دستگاه های مایکروویو، تماس با چاپ، دستگاه های الکتروشیمیایی کاغذی، تشخیص الکتروشیمیایی، الکترودهای کشیده مداد
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• A very simple, reliable, and inexpensive method for fabricating μPADs is proposed.
• PDMS was utilized to construct the hydrophobic barriers.
• PDMS barriers were able to contain some organic solvents and surfactant solutions.
• μPADs were tested in electroanalytical chemistry using aqueous and organic mediums.

This paper presents a simple and low-cost method for patterning poly(dimethylsiloxane) (PDMS) barriers in porous support such as paper for the construction of flexible microfluidic paper-based analytical devices (μPADs). The fabrication method consisted of contact-printing a solution of PDMS and hexane (10:1.5 w/w) onto chromatographic paper using custom-designed rubber stamps containing the patterns of μPADs. After penetrating the paper (∼30 s), the PDMS is cured to form hydrophobic barriers. Under optimized conditions, hydrophobic barriers and hydrophilic channels with dimensions down to 949 ± 88 μm and 771 ± 90 μm (n = 5), respectively, were obtained. This resolution is well-suitable for most applications in analytical chemistry. Chemical compatibility studies revealed that the PDMS barriers were able to contain some organic solvents, including acetonitrile and methanol, and aqueous solutions of some surfactants. This find is particularly interesting given that acetonitrile and methanol are the most used solvents in chromatographic separations, non-aqueous capillary electrophoresis and electroanalysis, as well as aqueous solutions of surfactants are suitable mediums for cell lyses assays. The utility of the technique was evaluated in the fabrication of paper-based electrochemical devices (PEDs) with pencil-drawn electrodes for experiments in static cyclic voltammetry and flow injection analysis (FIA) with amperometric detection, in both aqueous and organic mediums.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Analytica Chimica Acta - Volume 858, 9 February 2015, Pages 82–90
نویسندگان
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