کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1166302 | 1491113 | 2012 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Statistical mixture design selective extraction of compounds with antioxidant activity and total polyphenol content from Trichilia catigua Statistical mixture design selective extraction of compounds with antioxidant activity and total polyphenol content from Trichilia catigua](/preview/png/1166302.png)
Statistical design mixtures of water, methanol, acetone and ethanol were used to extract material from Trichilia catigua (Meliaceae) barks to study the effects of different solvents and their mixtures on its yield, total polyphenol content and antioxidant activity. The experimental results and their response surface models showed that quaternary mixtures with approximately equal proportions of all four solvents provided the highest yields, total polyphenol contents and antioxidant activities of the crude extracts followed by ternary design mixtures. Principal component and hierarchical clustering analysis of the HPLC–DAD spectra of the chromatographic peaks of 1:1:1:1 water–methanol–acetone–ethanol mixture extracts indicate the presence of cinchonains, gallic acid derivatives, natural polyphenols, flavanoids, catechins, and epicatechins.
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► Statistical design mixtures was used to extract material from Trichilia catigua barks.
► Quaternary mixtures are efficient for studying total polyphenol content and antioxidant activity.
► Comparative study of the HPLC–DAD spectra indicated different types of characteristic spectra.
Journal: Analytica Chimica Acta - Volume 719, 16 March 2012, Pages 57–60