کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1169663 | 960645 | 2008 | 8 صفحه PDF | دانلود رایگان |

In a first step towards chemical sensors using molecular imprinted materials, the complexing characteristics of diethyl 4-nitrobenzylphosphonate, an organophosphate pesticide analogue, have been studied. Two molecules have been assessed as potential interacting moieties, specifically a fluoroalcohol and an aromatic acid. The interactions have been first characterized by regular methods, such as 1H, 31P NMR and IR spectroscopy. These showed a stoichiometry 1/1 for both complexes and association constants, respectively, close to 40 ± 10 and 12 ± 2 M−1. In a second step, isothermal titration calorimetry was used and a method was developed to obtain low-association constants. The association constant could be obtained for the fluoroalcohol ligand and was found equal to 63 ± 0.7 M−1. For the acidic molecule, an appropriate model could not be found, preventing the evaluation of this constant.
Journal: Analytica Chimica Acta - Volume 614, Issue 1, 28 April 2008, Pages 63–70