کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1170195 | 960670 | 2007 | 11 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Novel analytical procedures for screening of drug residues in water, waste water, sediment and sludge Novel analytical procedures for screening of drug residues in water, waste water, sediment and sludge](/preview/png/1170195.png)
Traces of pharmaceuticals are continuously introduced into the aquatic environment mainly by sewage treatment plant effluents. Final data about their impact on the ecosystem are still partly missing. Progress in instrumental analytical chemistry has resulted in the availability of methods that allow a monitoring of these pollutants at ng L−1 levels. In this review the state-of-the-art of residue analysis of pharmaceuticals by chromatographic and electrophoretic techniques is summarized. Improvements in detection limits over the past years have mainly been due to sophisticated mass spectrometric detection techniques. Furthermore, robust sample preparation and preconcentration protocols based on solid-phase extraction and related procedures have contributed significantly to the achievements observed so far. This review also covers several immunochemical approaches which may serve as an inexpensive alternative for quick screening of samples.
Journal: Analytica Chimica Acta - Volume 593, Issue 2, 19 June 2007, Pages 129–139