A data base for polymer chromatography: Dependence of interaction parameters on mobile phase composition

In chromatography of polymers, retention is determined by the characteristic volumes of the column (pore volume and interstitial volume), the pore diameter, and the interaction parameter. While the influence of the pore diameter is predominant in size exclusion chromatography, the key parameters in liquid adsorption chromatography are the interaction parameter and the pore surface of the column. It is shown, that the retention behaviour of polymers in liquid adsorption chromatography (LAC) can be predicted very well using the accessible volume and pore surface of the column, which can be determined very easily, and the interaction parameters from a data base.