کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1171557 | 960724 | 2007 | 5 صفحه PDF | دانلود رایگان |
The compatibility Teflon-AF 2400 liquid core optical fibre with resonance Raman spectroscopy (RRS-LCOF) was used to detect aqueous biomolecules. The maximum sensitivity enhancement factor for concentrations greater than the detection limit in a conventional cell was 10, and detection limit reduction of about 1000-fold have been achieved for the measurement of aqueous absorbing sample using Teflon-AF 2400 fibre Raman cell compared to the conventional cell. We were able to collect spectra of 2.5 × 10−9 and 2.5 × 10−10 M aqueous β-carotene using 16.2 mW of laser power and 10 s integration time. This volume of a 2.5 × 10−10 M aqueous solution corresponds to only 1.5 fmol or 830 fg of β-carotene. The results of this preliminary study indicate that RRS-LCOF has potential in bioanalytical and biomedical applications.
Journal: Analytica Chimica Acta - Volume 581, Issue 1, 2 January 2007, Pages 154–158