کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1185955 | 963420 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
DNA binding studies of 2-tert-butylhydroquinone (TBHQ) food additive
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
The interaction of native calf thymus DNA with 2-tert-butylhydroquinone (TBHQ) in 10 mM Tris–HCl aqueous solutions at neutral pH 7.4, has been investigated by spectrophotometric, spectrofluorometric, voltammetric and viscosimetric techniques. It is found that TBHQ molecules could intercalate between base pairs of DNA as are evidenced by: hyperchromism in UV absorption band of DNA, sharp increase in specific viscosity of DNA and decrease in the fluorescence of TBHQ solutions in the presence of increasing amounts of DNA. Also peak current decrease, positive shift in the cyclic voltammetry (CV) and differential pulse voltammetry (DPV) are other evidences to indicate that, TBHQ is able to be intercalated in the DNA base pairs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 116, Issue 3, 1 October 2009, Pages 743–747
Journal: Food Chemistry - Volume 116, Issue 3, 1 October 2009, Pages 743–747
نویسندگان
S. Kashanian, J. Ezzati Nazhad Dolatabadi,