کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1199415 1493567 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Solid supported in situ derivatization extraction of acidic degradation products of nerve agents from aqueous samples
ترجمه فارسی عنوان
جداسازی مواد جامد از محلول های اسیدی از مواد معدنی عصبی از نمونه های آبی به طور ممتد پشتیبانی می شود
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی

This study deals with the solid supported in situ derivatization extraction of acidic degradation products of nerve agents present in aqueous samples. Target analytes were alkyl alkylphosphonic acids and alkylphosphonic acids, which are important environmental signatures of nerve agents. The method involved tert-butyldimethylchlorosilane mediated in situ silylation of analytes on commercially available diatomaceous solid phase extraction cartridges. Various parameters such as derivatizing reagent, its concentration, reaction time, temperature and eluting solvent were optimized. Recoveries of the analytes were determined by GC–MS which ranged from 60% to 86%. The limits of detection (LOD) and limit of quantification (LOQ) with selected analytes were achieved down to 78 and 213 ng mL−1 respectively, in selected ion monitoring mode. The successful applicability of method was also demonstrated on samples of biological origin such as plasma and to the samples received in 34th official proficiency test conducted by the Organization for Prohibition the of Chemical Weapons.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1359, 12 September 2014, Pages 325–329
نویسندگان
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