کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1200934 | 1493627 | 2013 | 5 صفحه PDF | دانلود رایگان |

• Simple sample preparation technique for microliter volume samples.
• Solventless micropurification using a commercial capillary electrophoresis instrument.
• Selective extraction of cationic or anionic charged species.
• Extraction of cationic and analysis of neutral species.
Cationic or anionic molecules can be selectively injected from an aqueous mixture of charged and neutral species into a capillary by electrophoresis. Under stacking conditions, this selective field enhanced sample injection was studied here as a potential sample preparation technique for the clean-up or purification of microliter samples. As a simple demonstration, cationic small molecules were removed or extracted from a 100 μL sample mixture using a commercial capillary electrophoresis instrument. The extraction was monitored using an on-line UV detector. Results from the micellar electrokinetic chromatography analysis of treated and untreated sample revealed significant reduction of cationic species in the treated sample. The technique is essentially a sequence of field enhanced sample injection experiments in capillary electrophoresis.
Journal: Journal of Chromatography A - Volume 1299, 19 July 2013, Pages 131–135