Quantifying temperature and flow rate effects on the performance of a fixed-bed chromatographic reactor

► Heterogeneously catalyzed hydrolysis reactions in a fixed-bed chromatographic reactor packed with a strong acidic ion exchange resin. ► An isothermal equilibrium dispersive model used for simulations. ► Essential model parameters determined experimentally and kinetic parameters estimated by fitting curves. ► The work provides insight regarding the influence of temperature and flow rate on the model parameters and the performance criteria.