کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1204974 | 1493714 | 2008 | 17 صفحه PDF | دانلود رایگان |
Simulated moving bed (SMB) chromatography is an important technique for the continuous separation of valuable products. Recently suggested process modifications have shown the potential for further improvement. In this work, a concept is presented that combines non-permanent product withdrawal at one or both outlet ports (leading periodically to a “product” and a “non-product” fraction) with an internal recycle and re-feeding of the “non-product” fraction in alternation to the original feed mixture. Using simulation studies for linear and non-linear isotherms, it was shown that in terms of process performance and product recovery, this fractionation and feed-back approach (FF-SMB) is superior to both the conventional SMB process as well as to a previously reported fractionation and discard strategy.
Journal: Journal of Chromatography A - Volume 1207, Issues 1–2, 17 October 2008, Pages 55–71