Applications of the chromatographic impulse response method in supercritical fluid chromatography

The use of chromatographic impulse response (CIR) method with a coated open tubular capillary column has potential advantages in supercritical fluid chromatography. In this review, applications of the CIR method to measuring the thermodynamic properties such as diffusion coefficients, solubilities and partial molar volumes are presented. This survey gives the theoretical backgrounds for the CIR method with linear adsorption and nonlinear adsorption models. Furthermore, the brief theoretical backgrounds for using retention factors to determine solubilities and partial molar volumes are also provided. In addition, the data sources for the diffusion coefficients with an emphasis on the results published after 2004 and for the partial molar volumes in supercritical carbon dioxide are presented.

► Theoretical background for the CIR method with linear adsorption model.
► Theoretical background for the CIR method with nonlinear adsorption model.
► Theoretical background for measuring solubility from retention factor.
► Theoretical background for measuring partial molar volume from retention factor.
► Brief review the diffusion data since 2005 and the partial molar volume data.