کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1205927 | 965212 | 2009 | 9 صفحه PDF | دانلود رایگان |

An ultra-high-performance liquid chromatography/time-of-flight mass spectrometry (with negative ion electrospray ionization) methodology was developed for the simultaneous quantification of benzoic acid and 15 long-chain monocarboxylic acids (MCAs) in ambient aerosols. A fast and quantitative pressurized fluid extraction procedure was optimized using experimental design and the extracts were analyzed without any further clean-up step. Chromatographic separation was achieved on a BEH-C18 column with a mobile phase consisting of 5 mM formic acid in water/acetonitrile (90:10, v/v) and methanol. Excellent precision and accuracies in the MS mass measurements were observed. The method was validated using actual samples spiked with a solution containing either standards or 13C-surrogates. Matrix effects were observed for the C14 MCA only. It was then applied to air particulate reference materials and atmospheric samples collected by a low-volume sampler.
Journal: Journal of Chromatography A - Volume 1216, Issue 37, 11 September 2009, Pages 6481–6489