کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1207225 1493713 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Simultaneous determination of 5-nitroimidazoles and nitrofurans in pork by high-performance liquid chromatography–tandem mass spectrometry
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Simultaneous determination of 5-nitroimidazoles and nitrofurans in pork by high-performance liquid chromatography–tandem mass spectrometry
چکیده انگلیسی

A simple and specific method has been developed for the simultaneous determination of four 5-nitroimidazoles and their two corresponding metabolites and four nitrofurans in pork. The sample preparation procedure was based on a simple solvent extraction/derivatization combined with solid-phase extraction (SPE) cleanup. The target compounds were identified and quantitatively determined by high-performance liquid chromatography (HPLC) coupled with electrospray ionization tandem mass spectrometry (ESI/MS/MS) operated in multiple reaction monitoring mode. The overall corrected recoveries ranged between 93 and 106%, with relative standard deviations (RSDs) of 7–13% for the entire procedure. The detection limits of the method for the 10 compounds under study ranged from 0.01 to 0.2 μg/kg.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1208, Issues 1–2, 24 October 2008, Pages 101–108
نویسندگان
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