کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1209465 | 1493757 | 2006 | 8 صفحه PDF | دانلود رایگان |
A restricted access media-molecularly imprinted polymer (RAM-MIP) for [2H16]bisphenol A (BPA-d16) was prepared by a multi-step swelling and polymerization method using 4-vinylpyridine as a functional monomer and ethylene glycol dimethacrylate as a cross-linker, followed by hydrophilic surface modification using glycerol dimethacrylate and glycerol monomethacrylate as hydrophilic monomers. The obtained RAM-MIP showed excellent molecular recognition abilities for BPA and BPA-d6 as well as BPA-d16 used as the template molecule, and good ones for tetrachlorobisphenol A (Cl4-BPA) and tetrabromobisphenol A (Br4-BPA). Next, the RAM-MIP was utilized for selective on-line pretreatment and enrichment of BPA, Cl4-BPA and Br4-BPA in a river water sample, followed by their separation and determination by LC–MS. The calibration graphs of BPA, Cl4-BPA and Br4-BPA, constructed using BPA-d6 as an internal standard, showed good linearity in the range of 12.5–200 pg/mL (r > 0.999) with a 2-mL injection of a river water sample. The inter-day precision data for the assay of BPA, Cl4-BPA and Br4-BPA at 25 pg/mL were 1.08, 3.67 and 1.58%, respectively. Furthermore, this method was successfully applied for the simultaneous determination of BPA and its halogenated derivatives in river water.
Journal: Journal of Chromatography A - Volume 1134, Issues 1–2, 17 November 2006, Pages 16–23