کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1210079 1493775 2006 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Miniaturized thermal lens and fluorescence detection system for microchemical chips
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Miniaturized thermal lens and fluorescence detection system for microchemical chips
چکیده انگلیسی

We have developed a miniaturized two-way detection system using thermal lens and fluorescence spectroscopies for microchip chemistry. The system was composed of laser diode (LD) modules, fiber-based optics combined with a gradient index lens, and miniaturized detection units for thermal lens and fluorescence signals. The detection limits in the thermal lens and fluorescence spectroscopies were 6.3 × 10−9 M for Ni(II) phthalocyanine tetrasulfonic acid and 3.0 × 10−9 M for cy5, respectively. The performance of the system with the miniaturized thermal lens was equivalent to that of a conventional thermal lens microscope. The fluorescence sensitivity was comparable to sensitivities offered by conventional miniaturized systems.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1106, Issues 1–2, 17 February 2006, Pages 89–93
نویسندگان
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