کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1210119 1493776 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Analysis of perfluorooctanesulfonate and related fluorochemicals in water and biological tissue samples by liquid chromatography–ion trap mass spectrometry
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Analysis of perfluorooctanesulfonate and related fluorochemicals in water and biological tissue samples by liquid chromatography–ion trap mass spectrometry
چکیده انگلیسی

A method for the determination of perfluorinated compounds (PFCs) in various water and biological tissue samples was developed and validated. The contents of selected PFCs (i.e., perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA) and perfluorodecanoate (PFDA)) in water samples were extracted by the C18 solid-phase extraction (SPE). The biological tissue samples (frozen-dried fish and oysters) were simply extracted by liquid–solid extraction with MTBE and adding tetrabutylammonium hydrogensulfate (TBA) as an ion-pairing reagent. The analytes were then identified and quantitated by liquid chromatography–ion trap negative electrospray mass spectrometry (LC–ESI ion-trap-MS). Limits of quantitation (LOQ) were established between 0.5 and 6 ng/l in 250 ml of water sample, while 5–50 ng/g (dry weight) for biological tissue sample. Intrabatch and interbatch precision with their accuracy at two concentration levels were also investigated. Precision for these three PFCs, as indicated by RSD, proved to be less than 11 and 17%, respectively. The total contents of PFOA, PFOS and PFDA were detected in concentrations of up to 400 ng/l in various water samples, while up to 1100 ng/g in fish and oyster samples. PFOA and PFDA was the major PFCs detected in water samples and biological tissue samples, respectively.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1105, Issues 1–2, 10 February 2006, Pages 119–126
نویسندگان
, , , ,