کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1210225 1493769 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Theoretical calculation of the retention enthalpy effect on the viscous heat dissipation band broadening in high performance liquid chromatography columns with a fixed wall temperature
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Theoretical calculation of the retention enthalpy effect on the viscous heat dissipation band broadening in high performance liquid chromatography columns with a fixed wall temperature
چکیده انگلیسی
The problem of the additional band broadening arising from the trans-column temperature profile under conditions of significant viscous heat dissipation has been extended by including the retention enthalpy effect. This effect can significantly aggravate the trans-column migration velocity profile of retained species as compared to the already known zero-retention enthalpy case. An approximate analytical solution for the accompanying additional band broadening could be established. The solution is valid in nearly all practically relevant cases and shows how the additional band broadening varies as a function of the generated heat, the retention coefficient and the retention enthalpy. Surveying all possible HPLC operating conditions, it was found that the inclusion of the retention enthalpy effect leads to significantly larger viscous heating plate height contributions than those predicted by the zero-retention enthalpy solution (up to a factor of 10 or more).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1116, Issues 1–2, 26 May 2006, Pages 89-96
نویسندگان
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