کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1214043 | 966915 | 2010 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Determination of iodide in urine using electrospray ionization tandem mass spectrometry Determination of iodide in urine using electrospray ionization tandem mass spectrometry](/preview/png/1214043.png)
A rapid and sensitive electrospray ionization (ESI) tandem mass spectrometry (MS–MS) procedure was developed for the determination of iodide (I−). A gold (Au) and I− complex was formed immediately after the addition of the chelating agent NaAuCl4 to I− solution, and was extracted with methyl isobutyl ketone. One to five microliters of the extract were injected directly into an ESI–MS–MS instrument. I− quantification was performed by selecting reaction monitoring of the product ion I− at m/z 127 derived from the precursor ion 197AuI2− at m/z 451. I− concentration was measured in the quantification range from 10−7 to 10−5 M using 50 μL of solution within 10 min. Iodate was reduced to I− with ascorbic acid and determined. I− concentration in reference urine 2670a was measured after treatments.
Journal: Journal of Chromatography B - Volume 878, Issue 20, 15 June 2010, Pages 1683–1686