The solubility parameter for biomedical polymers—Application of inverse gas chromatography

• Solubility parameter of PCL, PLA and PEG can be estimated by using IGC technique.
• Values of solubility parameter differ depending on the calculation procedure.
• Calculation of HSP enables detailed characteristic of the examined materials.

The solubility parameter seems to be a useful tool for thermodynamic characterisation of different materials. The solubility parameter concept can be used to predict sufficient miscibility or solubility between a solvent and a polymer, as well as components of co-polymer matrix in composite biomaterials.The values of solubility parameter were determined for polycaprolactone (PCL), polylactic acid (PLA) and polyethylene glycol (PEG) by using different procedures and experimental data, collected by means of inverse gas chromatography.