کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1221395 1494634 2014 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Magnetic separation techniques in sample preparation for biological analysis: A review
ترجمه فارسی عنوان
تکنیک های جداسازی مغناطیسی در تهیه نمونه برای تجزیه و تحلیل بیولوژیکی: بررسی
کلمات کلیدی
جداسازی مغناطیسی، آماده سازی نمونه، تجزیه و تحلیل بیولوژیکی، ماکرومولکول های بیولوژیکی، ترکیبات بیولوژیکی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی


• Magnetic separation techniques for biological sample preparation were reviewed.
• The preparation of magnetic nanoparticles was reviewed.
• The trends of magnetic separation techniques in biological analysis were proposed.

Sample preparation is a fundamental and essential step in almost all the analytical procedures, especially for the analysis of complex samples like biological and environmental samples. In past decades, with advantages of superparamagnetic property, good biocompatibility and high binding capacity, functionalized magnetic materials have been widely applied in various processes of sample preparation for biological analysis. In this paper, the recent advancements of magnetic separation techniques based on magnetic materials in the field of sample preparation for biological analysis were reviewed. The strategy of magnetic separation techniques was summarized. The synthesis, stabilization and bio-functionalization of magnetic nanoparticles were reviewed in detail. Characterization of magnetic materials was also summarized. Moreover, the applications of magnetic separation techniques for the enrichment of protein, nucleic acid, cell, bioactive compound and immobilization of enzyme were described. Finally, the existed problems and possible trends of magnetic separation techniques for biological analysis in the future were proposed.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 101, December 2014, Pages 84–101
نویسندگان
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