کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1221512 | 1494638 | 2014 | 5 صفحه PDF | دانلود رایگان |
• Brownish powder of cinnamon odor against rheumatic diseases purchased from the internet.
• 1H NMR and LC/MS revealed acetaminophen, trimethoprim, sulfamethoxazole and indomethacin as active pharmaceutical ingredients.
• Cinnamon bark was identified by light microscopy.
• Selling these sachets is illegal because it consists of prescription drugs.
Counterfeit and/or illegally manufactured drugs and herbal medicines are becoming an increasing problem throughout the world. Internet sales simplify distribution and payment of these falsified drugs. Here we report on a Vietnamese herbal medicine, which was advertised for treatment of rheumatic disease from a religious Vietnamese healer. By means of NMR and LC/MS we found 863 mg acetaminophen, 262 mg sulfamethoxazole, 42 mg indomethacin and less than 1% trimethoprim in a sachet of 2.617 g powder content, in addition to some cinnamon bark and phosphate.
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Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 97, 25 August 2014, Pages 24–28