Simultaneous determination of montelukast as sparing therapy with some inhaled corticosteroids in plasma of asthmatic patients

► Fast and efficient HPLC method for simultaneous determination of montelukast (MKST) when used as sparing therapy with some inhaled corticosteroids (ICS) in plasma of asthmatic patients. ► Use of monolith column. ► Application in real cases. ► Analytical control of effective tapering of ICS therapy with MKST in patients with chronic asthma in clinical practice.