کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1222199 | 1494666 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Isolation and structural elucidation of abietic acid as the main adulterant in an herbal drug for the treatment of psoriasis
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
An herbal drug for the treatment of psoriasis showed severe clinical adverse reactions. The main component of adulterant was isolated from the drug and its chemical structure was elucidated as abietic acid using NMR, HR–MS, and HPLC–DAD–MS. Although abietic acid had ever been used in clinical study for the treatment of psoriasis, it is not an approved drug. Its adulteration is very dangerous for the patients.
► The main component of adulterant was isolated from an herbal drug.
► Its chemical structure was elucidated as abietic acid.
► The adulteration of abietic acid is dangerous for the patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 66, July 2012, Pages 345–348
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 66, July 2012, Pages 345–348
نویسندگان
Yi He, Yumei Zhang, Jing Lu, Ruichao Lin,