کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1224354 967920 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
High-performance liquid chromatographic method for the quantification of phenolics in ‘Chyavanprash’ a potent Ayurvedic drug
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
High-performance liquid chromatographic method for the quantification of phenolics in ‘Chyavanprash’ a potent Ayurvedic drug
چکیده انگلیسی

Quantification of bioactive principles through modern analytical tools is essential for establishing the authenticity, creditability, prescription and usage of Ayurvedic medicines/herbal formulations. ‘Chyavanprash’ is one of the oldest and most popular Ayurvedic preparations, used widely as a health promotive and disease preventive ‘Rasayana’ drug in India and elsewhere. The rejuvenating and tonic properties of ‘Chavanprash’ are considered majorly due to their antioxidant principles, which in turn is due to the presence of phenolic compounds. A simple high-performance liquid chromatography (HPLC) method for the separation and quantitative determination of the major antioxidant compounds from ‘Chyavanprash’ has been developed. The use of Waters Symmetry® column and an acidic mobile phase enabled the efficient separation of phenolic compounds (catechin, quercetin-3-O-rutinoside, syringic acid and gallic acid) within a 35 min analysis. Validation of the method was done with a view to demonstrate its selectivity, linearity, precision, accuracy and robustness. In addition optimization of the complete extraction of phenolic compounds were also studied.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 43, Issue 2, 17 January 2007, Pages 527–532
نویسندگان
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