کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1224354 | 967920 | 2007 | 6 صفحه PDF | دانلود رایگان |

Quantification of bioactive principles through modern analytical tools is essential for establishing the authenticity, creditability, prescription and usage of Ayurvedic medicines/herbal formulations. ‘Chyavanprash’ is one of the oldest and most popular Ayurvedic preparations, used widely as a health promotive and disease preventive ‘Rasayana’ drug in India and elsewhere. The rejuvenating and tonic properties of ‘Chavanprash’ are considered majorly due to their antioxidant principles, which in turn is due to the presence of phenolic compounds. A simple high-performance liquid chromatography (HPLC) method for the separation and quantitative determination of the major antioxidant compounds from ‘Chyavanprash’ has been developed. The use of Waters Symmetry® column and an acidic mobile phase enabled the efficient separation of phenolic compounds (catechin, quercetin-3-O-rutinoside, syringic acid and gallic acid) within a 35 min analysis. Validation of the method was done with a view to demonstrate its selectivity, linearity, precision, accuracy and robustness. In addition optimization of the complete extraction of phenolic compounds were also studied.
Journal: Journal of Pharmaceutical and Biomedical Analysis - Volume 43, Issue 2, 17 January 2007, Pages 527–532